"A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695)." [PMID:10637607, PMID:17337012, PMID:19056896, PMID:20838651, PMID:33004486]
There are 281 sequences with this label.
Name | Species | % in cluster | p-value | corrected p-value | action |
---|---|---|---|---|---|
Cluster_161 | Chlamydomonas reinhardtii | 1.18 % | 0.004791 | 0.044033 | |
Cluster_181 | Physcomitrella patens | 1.2 % | 0.002557 | 0.029482 | |
Cluster_132 | Zygnema circumcarinatum | 1.35 % | 0.003668 | 0.032249 |