GO:0000124: SAGA complex (Cellular component)

"A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695)." [PMID:10637607, PMID:17337012, PMID:19056896, PMID:20838651, PMID:33004486]


There are 281 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_161 Chlamydomonas reinhardtii 1.18 % 0.004791 0.044033
Cluster_181 Physcomitrella patens 1.2 % 0.002557 0.029482
Cluster_132 Zygnema circumcarinatum 1.35 % 0.003668 0.032249
Sequences (281) (download table)

InterPro Domains

GO Terms

Family Terms