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GO:0004222: metalloendopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE]


There are 1783 sequences with this label.



Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_34 Arabidopsis thaliana 2.5 % 0.002768 0.0088
Cluster_185 Arabidopsis thaliana 1.44 % 0.008108 0.021659
Cluster_153 Chlamydomonas reinhardtii 1.6 % 0.007786 0.021371
Cluster_170 Chlamydomonas reinhardtii 3.85 % 0.001396 0.01912
Cluster_95 Marchantia polymorpha 3.85 % 0.000211 0.013307
Cluster_51 Marchantia polymorpha 4.21 % 1.2e-05 0.000358
Cluster_130 Zygnema circumcarinatum 2.99 % 0.005052 0.027238
Sequences (1783) (download table)



Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains



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