GO:0005242: inward rectifier potassium channel activity (Molecular function)

"Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself." [GOC:cb, GOC:mah, PMID:14977398]


There are 407 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Sequences (407) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms