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View using InCHLib : here ( Experimental feature, still under development)
(Values are log2 transformed ratios of a genes expression in a sample divided by the mean expression level)
| Gene | Archegoniophore (female) | Antheridiophore (male) | Antheridium (male) | Sperm | Sporeling | Thallus | Thallus (vegetative) | Thallus (MpPAP1OX-1) | Thallus (Tak1-2) | Thallus (MpPAP1OX-3) | Thallus (MpPAP1OX-2) | Thallus (Tak1-3) | mid rib (male) | Gametophyte | Gemmaling (female, hpt2040) | Gemmaling (male, hpt2040) | Gemmaling (BC3-38) | Gemmaling (Tak1) | Gemmaling | Gemma cup | gemma cup (male) | Aseptically grown rhizoids, thalloid, gemmae | Control | Cold (3°C) | Dark (3 days) | Heat (33°C) | Light (435 uEm-2s-1) | Osmotic (100 mM mannitol) | Nitrogen deficiency (0 mM KNO3) | Salt (40 mM NaCl) | Cold-Dark | Cold-Light | Cold-Mannitol | Cold-Nitrogen deficiency | Cold-Salt | Heat-Dark | Heat-Mannitol | Heat-Nitrogen deficiency | Heat-Salt | Light-Salt | Mannitol-Dark | Mannitol-Light | Mannitol-Nitrogen deficiency | Nitrogen deficiency-Dark | Nitrogen deficiency-Light | Salt-Dark | Salt-Mannitol | Salt-Nitrogen deficiency | ZT2 (2 hours after light) | ZT6 (6 hours after light) | ZT10 (10 hours after light) | ZT14 (2 hours after dark) | ZT18 (6 hours after dark) | ZT22 (10 hours after dark) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| -1.8 | 0.53 | 2.89 | -1.09 | -1.45 | -2.59 | -1.63 | - | - | -0.43 | - | - | -0.68 | -3.91 | -1.89 | - | -0.93 | - | - | -1.57 | - | -1.2 | -0.71 | -1.32 | 1.08 | 1.27 | -2.19 | -0.98 | -1.96 | -0.73 | 1.14 | 0.24 | -2.97 | -1.39 | -2.13 | 2.49 | -0.04 | 0.83 | 0.9 | -1.5 | 2.12 | -0.77 | -2.44 | 2.57 | -0.67 | 1.9 | -1.93 | -0.18 | -2.12 | -0.97 | -2.25 | -1.95 | -1.3 | -0.93 | |
| 0.12 | 0.82 | 1.39 | -6.32 | -0.35 | -0.69 | 0.19 | -0.29 | 0.17 | -0.27 | -0.17 | -0.02 | -1.11 | -0.55 | -0.43 | -0.5 | -0.54 | -0.52 | -0.17 | -0.57 | -0.62 | -0.42 | -0.29 | -0.48 | 0.66 | -0.06 | -0.2 | -0.32 | -0.19 | -0.45 | 0.19 | -1.07 | -0.52 | -0.43 | -0.6 | 1.33 | -0.17 | 0.16 | -0.15 | -0.24 | 1.35 | -0.32 | -0.43 | 0.89 | 0.02 | 1.46 | -0.41 | -0.3 | -0.43 | -0.45 | -0.27 | -0.18 | 0.34 | 0.37 | |
| -1.14 | -0.98 | 3.05 | 1.5 | -3.06 | -1.35 | -0.71 | - | - | 1.07 | 0.99 | - | -1.49 | -2.98 | - | 0.1 | - | - | - | 0.3 | 0.5 | 0.73 | -1.74 | - | 0.02 | 0.6 | 0.13 | -1.78 | -2.61 | -2.62 | - | 1.13 | -1.79 | -2.71 | -2.74 | 3.04 | -1.06 | 0.53 | -0.39 | -2.84 | -0.05 | -0.14 | - | 1.49 | 0.61 | 2.19 | -2.92 | -2.97 | - | -2.81 | -2.46 | -0.58 | -2.64 | -1.57 | |
| -0.38 | 0.56 | 1.32 | -1.51 | -1.2 | -0.19 | 0.49 | -0.21 | -0.58 | -0.74 | -1.44 | -0.76 | -2.08 | -0.71 | -0.37 | -0.56 | -0.16 | -0.66 | -0.44 | -0.15 | -0.17 | 0.35 | 0.21 | -0.79 | 0.92 | 0.37 | -0.14 | -0.64 | 0.28 | -0.39 | -0.43 | -1.17 | -0.35 | 0.26 | 0.04 | 0.43 | 0.16 | 0.56 | 0.28 | 0.38 | 1.15 | -0.38 | -0.31 | 1.44 | -0.1 | 0.9 | -0.48 | -0.28 | -0.28 | 0.09 | 0.09 | -0.17 | -0.33 | -0.18 | |
| -0.04 | 1.0 | 1.84 | -2.81 | 0.25 | 0.41 | 0.14 | 0.23 | 0.32 | 0.29 | 0.31 | 0.71 | -0.81 | -0.51 | -0.61 | -0.66 | -0.78 | -0.8 | -0.5 | 0.72 | 0.48 | 0.46 | -1.27 | -1.47 | 0.54 | -0.18 | -0.92 | -1.04 | -0.95 | -1.17 | -0.14 | -1.07 | -1.05 | -1.32 | -1.12 | 0.89 | 0.35 | 0.33 | 0.24 | -1.01 | 1.33 | -0.22 | -0.89 | 1.05 | -0.81 | 1.59 | -0.76 | -1.08 | -1.76 | -1.59 | -1.32 | -0.02 | 0.08 | -0.45 | |
| -0.03 | 0.11 | 0.67 | -3.15 | -0.02 | -0.6 | -0.0 | -0.12 | 0.21 | -0.13 | -0.11 | 0.18 | -0.79 | -0.19 | -0.63 | -0.71 | -0.61 | -0.71 | -0.01 | -0.35 | -0.51 | 0.08 | -0.12 | -0.57 | 0.73 | -0.12 | 0.07 | -0.18 | 0.01 | -0.24 | 0.31 | -0.85 | -0.45 | -0.35 | -0.59 | 1.34 | -0.15 | 0.33 | -0.16 | -0.25 | 1.01 | -0.18 | -0.29 | 0.67 | 0.08 | 1.39 | -0.3 | -0.27 | -0.26 | -0.22 | -0.12 | 0.1 | 0.27 | 0.16 | |
| 0.45 | 0.63 | 1.93 | -1.92 | -0.36 | 0.06 | 0.54 | -0.6 | 0.1 | -0.93 | -0.4 | 0.03 | -0.6 | -0.37 | -0.84 | -0.53 | -0.89 | -0.81 | -0.22 | -0.41 | -0.44 | -0.17 | -0.66 | -1.48 | 1.06 | 0.46 | -0.33 | -0.59 | -0.83 | -0.67 | 0.07 | -1.73 | -0.91 | -1.22 | -1.03 | 0.04 | 0.31 | 0.23 | 0.44 | -0.35 | 1.87 | -0.37 | -0.81 | 1.28 | -0.21 | 1.83 | -0.62 | -0.69 | -0.69 | -0.71 | -0.72 | -0.81 | -0.39 | -0.17 | |
| -0.74 | 1.25 | 2.65 | -1.04 | 0.84 | 0.78 | 0.05 | -0.71 | 0.05 | -0.61 | -0.47 | -0.01 | -1.85 | -0.9 | -0.41 | -0.71 | -0.38 | -0.49 | 0.3 | -0.17 | -0.43 | -0.38 | -0.49 | -1.68 | -0.09 | 0.0 | -0.82 | -0.06 | -0.44 | -0.51 | -1.19 | -1.71 | -1.1 | -1.87 | -1.56 | 0.53 | 0.26 | 0.29 | -0.04 | -0.58 | 1.45 | -0.41 | -0.28 | 0.86 | -0.83 | 1.19 | -0.59 | -0.82 | -0.42 | -0.31 | -0.62 | -0.34 | -0.04 | 0.01 | |
| 0.07 | 1.39 | 1.88 | -3.68 | 0.4 | 0.36 | -0.79 | -0.29 | -0.03 | -0.93 | -0.57 | 0.09 | -0.64 | -0.11 | -0.22 | -0.23 | -0.48 | -0.5 | 0.05 | -0.45 | -0.74 | -1.18 | -0.49 | -0.39 | 0.21 | 0.3 | -0.39 | -0.69 | -0.4 | -0.85 | 0.16 | -0.59 | -0.25 | -0.32 | -0.16 | 1.05 | -0.03 | 0.39 | 0.05 | -0.55 | 0.99 | 0.02 | -0.44 | 0.86 | -0.22 | 0.78 | -0.46 | -0.47 | -0.87 | -0.7 | -0.75 | 0.16 | 0.42 | 0.11 | |
| -2.49 | 0.41 | 2.46 | -1.29 | -3.42 | -0.76 | -1.66 | -4.07 | - | -0.65 | -0.57 | -1.15 | -1.15 | -0.89 | -2.13 | -1.57 | -2.65 | -2.2 | - | -1.26 | -0.95 | -1.46 | -0.05 | -1.26 | 1.38 | 0.32 | 0.56 | 0.23 | -0.41 | -0.22 | 0.84 | -0.19 | -0.51 | -0.58 | -0.26 | -0.21 | 0.77 | 0.62 | 0.31 | -0.13 | 1.32 | 1.02 | 0.29 | 1.15 | 0.44 | 0.91 | 0.59 | -0.61 | -0.43 | -0.94 | -0.51 | -0.33 | 0.8 | 1.0 | |
| 0.05 | 1.44 | 2.87 | -2.22 | -1.01 | -0.47 | 0.1 | -0.5 | -0.47 | -0.83 | -0.24 | -0.69 | -0.77 | -1.21 | -1.56 | -1.32 | -1.23 | -1.74 | -0.81 | -0.61 | -0.52 | -0.01 | -1.22 | -1.45 | 1.12 | 0.31 | -0.43 | -1.09 | -0.61 | -1.31 | -0.55 | -1.62 | -1.63 | -1.59 | -1.77 | 1.33 | 0.48 | 0.59 | 0.53 | -0.33 | 1.58 | -0.61 | -1.03 | 1.33 | -0.11 | 1.71 | -1.06 | -0.87 | -1.58 | -1.44 | -1.53 | -1.05 | 0.01 | 0.11 | |
| 0.84 | 1.49 | 2.67 | -3.51 | -1.21 | 0.02 | -0.16 | -0.56 | -0.12 | -0.38 | -0.39 | -0.01 | -1.58 | -0.07 | -1.07 | -1.16 | -1.21 | -1.08 | -0.59 | -0.22 | -0.42 | 0.12 | -1.18 | -0.4 | 0.25 | 0.02 | -0.36 | -0.66 | -0.57 | -0.73 | 0.32 | -0.8 | 0.05 | -0.38 | 0.02 | 0.83 | 0.25 | 0.26 | 0.02 | -0.47 | 1.31 | 0.12 | -0.59 | 0.73 | -0.13 | 1.15 | -0.32 | -0.48 | -1.18 | -1.15 | -1.28 | -1.19 | -0.89 | -0.89 | |
| -0.55 | 0.86 | 3.25 | 1.25 | -1.21 | -0.07 | -0.74 | -1.25 | -0.66 | -1.14 | -0.76 | -0.96 | -2.02 | -1.33 | -1.32 | -1.12 | -1.48 | -1.06 | -1.98 | -0.73 | -0.6 | -0.35 | -1.66 | -1.58 | 0.66 | -0.74 | -1.61 | -1.62 | -1.48 | -1.43 | 0.11 | -0.87 | -1.83 | -1.56 | -1.64 | 1.05 | -0.62 | -0.4 | -0.37 | -1.06 | 2.39 | -1.31 | -1.69 | 1.79 | -1.44 | 2.51 | -1.21 | -1.54 | -1.76 | -1.66 | -1.96 | -1.25 | -0.81 | -0.41 | |
| -1.85 | 0.05 | 3.15 | -5.28 | -2.48 | -4.03 | -3.65 | -1.31 | -1.75 | -2.21 | -1.3 | -2.12 | -1.79 | -1.89 | -3.65 | -3.71 | -3.7 | -3.33 | -1.92 | -2.25 | -1.44 | -5.01 | -0.56 | -0.47 | 2.08 | 1.18 | 0.3 | -0.82 | -1.19 | -1.36 | 1.36 | -0.14 | -0.98 | -0.71 | -0.85 | 0.29 | 1.09 | 0.44 | 0.67 | -0.43 | 1.86 | 0.17 | -1.12 | 2.09 | 0.35 | 1.08 | -0.67 | -1.47 | -0.98 | -2.06 | -1.48 | -1.31 | 0.03 | 0.08 | |
| -2.25 | - | 3.91 | 0.5 | -2.5 | -2.94 | - | - | - | - | - | - | - | -3.47 | - | - | - | - | - | - | - | - | -4.11 | -2.02 | 2.82 | - | - | - | - | - | 2.92 | -0.99 | -3.29 | - | - | -2.25 | - | - | -2.45 | - | 2.25 | -3.38 | - | 2.34 | -3.3 | 3.45 | - | - | - | - | - | - | - | -2.9 | |
| -2.54 | 0.52 | 2.19 | -1.95 | -3.2 | -0.24 | -1.97 | -1.77 | -1.82 | -0.63 | -0.92 | -0.29 | -1.35 | -2.01 | -1.64 | - | -1.78 | -2.42 | -0.67 | -0.82 | 0.0 | -1.18 | -0.82 | -1.12 | 0.77 | 1.18 | 0.1 | -0.23 | -1.71 | -0.79 | -0.21 | -1.38 | -1.23 | -1.94 | -1.31 | 1.15 | 1.55 | 0.9 | 0.96 | 0.65 | 1.8 | 0.25 | -1.26 | 1.79 | -0.09 | 1.78 | -0.24 | -1.03 | -0.47 | -0.46 | -1.85 | -0.6 | 0.24 | 0.32 | |
| -2.54 | 0.52 | 2.19 | -1.95 | -3.2 | -0.24 | -1.97 | -1.77 | -1.82 | -0.63 | -0.92 | -0.29 | -1.35 | -2.01 | -1.64 | - | -1.78 | -2.42 | -0.67 | -0.82 | 0.0 | -1.18 | -0.82 | -1.12 | 0.77 | 1.18 | 0.1 | -0.23 | -1.71 | -0.79 | -0.21 | -1.38 | -1.23 | -1.94 | -1.31 | 1.15 | 1.55 | 0.9 | 0.96 | 0.65 | 1.8 | 0.25 | -1.26 | 1.79 | -0.09 | 1.78 | -0.24 | -1.03 | -0.47 | -0.46 | -1.85 | -0.6 | 0.24 | 0.32 | |
| -0.95 | -0.15 | 1.46 | -1.63 | -2.83 | -1.51 | -0.45 | -0.95 | -1.59 | -4.41 | -1.64 | -0.64 | -1.38 | -1.21 | -1.84 | -2.55 | -1.63 | -1.1 | -1.61 | -0.71 | -1.35 | -4.12 | 0.24 | -0.49 | 0.66 | 1.39 | 0.12 | -0.21 | -0.04 | -0.38 | 1.17 | -0.73 | 0.17 | -0.05 | -0.06 | 0.85 | 0.67 | 1.44 | 1.04 | -0.38 | 1.5 | -0.01 | -0.76 | 1.05 | 0.43 | 1.34 | -0.85 | -0.03 | -0.6 | -0.47 | 0.17 | 0.49 | 0.41 | 0.25 | |
| -1.55 | -0.09 | 3.05 | 0.13 | -0.95 | 0.17 | 1.11 | -0.87 | 0.08 | -1.3 | -0.74 | 0.6 | -0.19 | -1.6 | -2.88 | -3.29 | -3.03 | -2.17 | -1.9 | -0.35 | -0.37 | 0.61 | -1.78 | -4.86 | 1.51 | -0.83 | -2.13 | -2.05 | -1.59 | -2.22 | -0.12 | -1.46 | -4.85 | -3.66 | -4.18 | 2.2 | -1.05 | -0.23 | -0.82 | -2.43 | 2.49 | -2.4 | -2.37 | 1.77 | -2.01 | 2.35 | -2.4 | -2.8 | -2.14 | -2.41 | -2.79 | -1.12 | -0.82 | -0.52 | |
| -0.94 | -0.71 | 1.8 | -1.83 | -0.85 | -0.85 | -9.28 | -0.99 | -1.37 | -0.69 | -1.0 | -0.36 | -1.45 | -2.4 | -1.2 | -1.19 | -1.1 | -1.02 | -0.58 | -1.01 | -1.22 | -1.57 | -0.17 | -0.69 | 0.76 | 0.95 | 0.11 | -0.04 | 0.22 | -0.18 | 0.25 | -0.18 | -0.59 | -0.26 | -0.36 | 1.45 | 0.51 | 0.91 | 0.55 | 0.15 | 0.97 | 0.28 | 0.02 | 0.91 | 0.54 | 1.28 | 0.09 | 0.17 | -0.17 | -0.13 | -0.02 | 0.01 | 0.47 | 0.46 | |
| -0.57 | 0.35 | 2.58 | -1.11 | -0.43 | 0.47 | 0.05 | -0.58 | 0.08 | -1.26 | -0.58 | -0.02 | -0.45 | -0.66 | -0.92 | -0.83 | -1.33 | -1.18 | -0.93 | -0.64 | -0.33 | -0.41 | -0.83 | -2.36 | 1.43 | -0.05 | -0.86 | -1.11 | -0.97 | -1.36 | 0.18 | -1.78 | -2.41 | -2.3 | -2.44 | 0.98 | -0.25 | -0.1 | -0.09 | -0.83 | 2.06 | -0.86 | -0.98 | 1.74 | -0.72 | 2.17 | -1.15 | -1.09 | -0.93 | -1.28 | -1.71 | -0.89 | 0.19 | 0.64 | |
| 0.44 | -0.99 | -0.73 | -2.54 | -4.69 | -1.12 | -1.54 | -4.62 | -1.36 | -2.29 | -2.62 | -2.73 | -2.58 | -1.81 | -5.31 | -4.44 | -1.18 | -1.02 | -3.12 | -2.44 | -1.27 | -0.8 | -0.17 | -0.42 | 1.03 | 0.9 | 0.47 | -0.45 | -0.6 | -0.75 | 1.57 | -0.36 | -0.31 | -0.42 | -0.44 | 0.76 | 0.75 | 2.06 | 0.92 | -0.41 | 1.8 | 0.93 | -0.76 | 1.56 | 0.81 | 1.84 | -0.31 | -0.25 | -0.26 | 0.17 | -0.25 | 0.14 | 0.15 | -0.47 | |
| 0.46 | 0.99 | 1.81 | -3.29 | 0.67 | 0.36 | 0.17 | -0.7 | 0.14 | -0.66 | -0.78 | 0.31 | -1.4 | -0.14 | -0.49 | -0.32 | -0.4 | -0.36 | -0.19 | 0.33 | 0.42 | 0.98 | -0.81 | -1.27 | 0.1 | 0.05 | -0.55 | -0.76 | -0.43 | -0.87 | -0.21 | -0.47 | -0.55 | -0.81 | -0.4 | 0.43 | 0.09 | 0.52 | -0.0 | -0.55 | 1.38 | 0.03 | -0.56 | 0.73 | -0.08 | 1.07 | -0.52 | -0.5 | -1.1 | -0.58 | -0.76 | -0.51 | -0.42 | -0.48 | |
| 0.14 | 0.72 | 1.18 | -6.2 | 0.19 | 0.09 | 0.43 | 0.05 | 0.39 | 0.04 | 0.05 | 0.36 | -0.42 | -0.68 | -0.39 | -0.41 | -0.32 | -0.29 | 0.19 | 0.14 | 0.17 | 0.31 | -0.4 | -0.55 | 0.87 | -0.12 | -0.23 | -0.57 | -0.35 | -0.7 | 0.45 | -0.52 | -0.72 | -0.45 | -0.59 | 0.6 | -0.28 | -0.0 | -0.32 | -0.54 | 0.94 | -0.47 | -0.74 | 0.83 | -0.22 | 0.99 | -0.7 | -0.58 | -0.78 | -0.68 | -0.54 | -0.0 | 0.33 | 0.37 | |
| -0.51 | - | - | 0.65 | -1.83 | -0.33 | 0.35 | - | - | - | - | - | - | -0.45 | - | -0.52 | -0.88 | - | - | - | - | 1.94 | -2.11 | -2.16 | 3.27 | 0.96 | - | - | - | - | 1.45 | -2.51 | -1.42 | - | -1.39 | 0.81 | 0.96 | 1.15 | 1.11 | - | 2.75 | -1.59 | - | 2.16 | - | 1.32 | 0.65 | -2.45 | - | -1.46 | -1.01 | 0.04 | -0.13 | 0.23 | |
| -0.08 | 0.72 | 1.93 | -1.75 | 0.09 | -0.53 | 0.16 | -0.21 | -0.14 | -0.36 | -0.44 | -0.08 | -0.4 | -0.32 | -0.28 | -0.41 | -0.36 | -0.35 | 0.08 | 0.02 | 0.02 | -0.1 | -0.3 | -0.19 | 0.46 | -0.3 | -0.38 | -0.25 | -0.1 | -0.42 | 0.49 | -0.39 | -0.01 | 0.1 | -0.12 | 1.04 | -0.46 | -0.19 | -0.4 | -0.31 | 0.75 | -0.28 | -0.23 | 0.64 | -0.16 | 0.8 | -0.11 | -0.05 | -0.57 | -0.23 | -0.13 | -0.45 | -0.57 | -0.66 | |
| 0.07 | 0.97 | 2.44 | -1.08 | -0.61 | -0.05 | -0.04 | -0.29 | -0.99 | -0.44 | 0.03 | -1.31 | -2.35 | -0.5 | -1.2 | -0.66 | -1.21 | -0.37 | -1.02 | -0.03 | -0.43 | -0.72 | -0.77 | -1.49 | 0.67 | 0.33 | -0.75 | -1.12 | -0.42 | -0.86 | 0.84 | -1.17 | -0.72 | -0.88 | -0.53 | 1.64 | 0.55 | 1.18 | 0.61 | 0.22 | 0.9 | -0.11 | -0.66 | 0.97 | 0.06 | 1.14 | -0.76 | -0.81 | -1.23 | -0.88 | -0.88 | -0.95 | -0.74 | -0.23 | |
| -4.59 | 2.15 | 3.3 | 0.25 | -0.12 | 0.2 | -3.57 | -1.19 | -0.25 | -1.07 | -0.72 | -0.72 | -2.47 | -4.9 | -0.68 | -2.3 | -1.06 | 0.06 | - | -2.0 | -0.84 | -3.2 | -1.27 | -2.62 | 1.58 | -0.49 | -1.28 | -0.47 | -2.51 | -0.81 | 0.11 | -0.47 | -2.16 | -4.1 | -2.72 | 0.54 | 0.13 | -0.62 | 0.21 | -0.36 | 1.61 | -2.29 | -2.05 | 1.4 | -1.48 | 2.02 | -1.44 | -1.42 | -1.05 | -0.75 | -0.81 | -0.24 | 0.38 | 0.38 | |
| 0.89 | 1.31 | 2.67 | -4.2 | -1.2 | -0.21 | -0.43 | -0.11 | 0.16 | -0.45 | -0.16 | 0.15 | -0.96 | -0.2 | -0.12 | -0.2 | -0.15 | -0.05 | 0.12 | -0.01 | 0.4 | -0.25 | -1.14 | -1.35 | 0.34 | -1.54 | -1.64 | -0.9 | -0.33 | -0.66 | -0.69 | -1.9 | -1.05 | -0.42 | -0.96 | 1.26 | -1.42 | -0.86 | -1.35 | -0.66 | 1.86 | -1.03 | -0.76 | 1.31 | -0.42 | 1.58 | -0.84 | -0.58 | -1.23 | -1.29 | -1.02 | -0.77 | -0.42 | -0.74 | |
| -0.81 | 0.31 | 1.79 | -1.93 | -0.66 | 0.03 | -0.27 | -0.58 | -0.38 | -1.16 | -0.69 | -0.48 | -2.13 | 0.3 | -0.94 | -0.56 | -0.74 | -0.64 | -0.55 | 0.1 | 0.29 | 0.73 | -0.39 | -0.95 | 0.09 | -0.64 | 0.89 | -0.04 | 0.01 | 0.11 | -0.51 | -0.23 | 0.02 | -0.6 | -0.27 | 0.92 | -0.05 | -0.27 | -0.24 | 0.39 | 0.98 | 0.75 | 0.18 | 0.49 | 0.47 | 1.07 | 0.72 | 0.1 | 0.14 | -0.39 | -0.6 | -1.13 | -0.85 | -1.0 | |
| -0.28 | 0.29 | 1.95 | -6.66 | -1.45 | -0.71 | -1.04 | -1.3 | -0.41 | -1.09 | -1.27 | -0.36 | -0.63 | -1.84 | -1.23 | -1.15 | -0.91 | -1.01 | -1.43 | -0.92 | -0.76 | -1.41 | -0.13 | -0.88 | 0.75 | 0.39 | -0.08 | -0.21 | 0.34 | -0.28 | -0.21 | -0.5 | -0.74 | -0.17 | -0.54 | 1.36 | 0.51 | 0.69 | 0.49 | -0.04 | 1.18 | 0.18 | 0.01 | 1.24 | 0.53 | 1.14 | -0.22 | 0.16 | -0.45 | -0.15 | -0.2 | 0.17 | 0.56 | 0.61 | |
| 0.04 | 2.03 | 3.23 | -2.29 | -0.01 | -0.82 | -0.98 | -1.45 | -0.91 | -1.4 | -1.07 | -1.04 | -2.17 | -2.11 | -0.93 | -1.05 | -1.35 | -1.1 | -1.0 | -0.75 | -1.09 | -2.77 | -0.38 | -1.16 | 1.46 | -0.99 | -0.39 | -0.57 | -0.55 | -0.93 | 1.05 | -2.16 | -0.86 | -1.0 | -1.07 | 0.81 | -1.09 | -0.95 | -1.25 | -1.47 | 1.37 | -0.35 | -0.39 | 1.35 | -0.51 | 1.32 | -0.54 | -0.54 | -0.55 | -0.36 | -0.25 | -0.24 | -0.03 | 0.14 | |
| 0.26 | 0.78 | 1.93 | -1.88 | -1.23 | -0.17 | 0.29 | -1.22 | 0.01 | -1.99 | -0.65 | -0.59 | -0.46 | -1.34 | -0.72 | -1.04 | -0.85 | -1.1 | -0.88 | -1.09 | -0.82 | -0.48 | -0.02 | -0.92 | 0.41 | 0.52 | 0.27 | -0.41 | 0.37 | -0.6 | 0.51 | -0.26 | -0.95 | -0.42 | -0.81 | 0.56 | 0.44 | 1.16 | 0.4 | 0.03 | 0.78 | -0.02 | -0.3 | 1.2 | 0.69 | 0.6 | -0.45 | -0.03 | -0.66 | -0.37 | -0.4 | 0.17 | 0.26 | 0.16 | |
| -1.04 | -0.99 | 1.74 | 0.22 | -1.45 | -0.54 | -1.07 | -1.41 | -0.91 | -1.78 | -1.12 | -0.55 | -1.28 | -1.89 | -1.59 | -1.35 | -1.56 | -1.71 | -2.19 | -0.97 | -0.93 | -0.72 | -0.01 | -1.18 | 1.02 | 0.85 | 0.49 | 0.17 | 0.09 | -0.04 | -0.19 | -0.76 | -0.91 | -0.87 | -0.86 | 0.8 | 1.03 | 0.83 | 1.12 | 0.38 | 1.43 | 0.66 | 0.18 | 0.83 | 0.1 | 1.18 | 0.25 | 0.11 | -0.23 | -0.25 | -0.3 | -0.24 | 0.35 | 0.43 | |
| 0.39 | 1.01 | 2.4 | -5.98 | -0.47 | 0.02 | 0.77 | -0.64 | 0.23 | -0.8 | -0.7 | -0.04 | -1.46 | -0.92 | -0.46 | -0.53 | -0.45 | -0.52 | -0.27 | -0.73 | -0.77 | -0.32 | -0.26 | -0.58 | 0.54 | -1.34 | -1.51 | -0.33 | -0.93 | -0.82 | 0.6 | -1.53 | -0.11 | -1.1 | -0.42 | 1.39 | -0.92 | -1.28 | -1.12 | -1.18 | 1.63 | -0.86 | -0.69 | 1.13 | -0.98 | 1.67 | -0.61 | -0.57 | -0.66 | -0.34 | -0.03 | -0.01 | 0.37 | 0.24 | |
| 0.01 | 1.06 | 2.56 | -1.96 | -0.06 | -0.18 | -0.55 | -1.14 | -0.84 | -1.12 | -1.09 | -0.69 | -1.14 | -0.73 | -1.52 | -1.39 | -1.68 | -1.54 | -0.71 | -0.81 | -1.14 | -1.04 | -0.42 | -0.71 | 0.96 | 0.19 | -0.4 | -0.43 | -0.29 | -0.59 | 0.65 | -0.65 | -0.2 | -0.29 | -0.55 | 1.29 | 0.16 | 0.21 | 0.09 | -0.2 | 1.14 | -0.17 | -0.3 | 1.2 | -0.01 | 1.59 | -0.29 | -0.36 | -0.82 | -0.47 | -0.27 | -0.32 | -0.13 | -0.34 | |
| 0.24 | 0.83 | 1.45 | -4.06 | 0.55 | 0.29 | -0.0 | -0.3 | -0.02 | -0.69 | -0.62 | 0.06 | -0.78 | -0.65 | -0.07 | -0.1 | -0.14 | -0.16 | 0.41 | -0.03 | -0.05 | -0.2 | -0.43 | -0.5 | 0.3 | 0.26 | -0.31 | -0.34 | -0.18 | -0.51 | -0.3 | -0.43 | -0.07 | -0.26 | -0.29 | 0.09 | 0.41 | 0.64 | 0.14 | -0.24 | 0.67 | -0.15 | -0.17 | 0.61 | -0.04 | 0.35 | -0.12 | -0.08 | -0.54 | -0.44 | -0.38 | -0.03 | 0.18 | -0.06 | |
| 0.18 | 0.46 | 2.55 | -1.7 | -0.01 | 0.02 | 0.2 | -0.08 | 0.81 | 0.7 | 0.18 | 1.43 | -2.27 | -0.44 | -2.45 | -1.87 | -2.64 | -2.44 | -2.23 | 0.59 | 0.15 | 0.05 | -2.1 | -1.59 | 1.14 | -1.11 | -0.88 | -2.6 | -2.13 | -2.5 | 1.64 | -0.81 | -0.71 | -1.28 | -0.84 | 1.75 | -1.19 | -0.91 | -1.44 | -2.12 | 1.6 | -0.45 | -1.9 | 1.36 | -1.48 | 1.6 | -2.21 | -2.42 | -1.46 | -1.22 | -1.32 | -0.3 | -0.69 | -0.23 | |
| 0.19 | 0.66 | 1.19 | -5.64 | -0.71 | -0.19 | 0.34 | -0.31 | 0.14 | -0.61 | -0.34 | 0.22 | -0.24 | -0.21 | -0.6 | -0.73 | -0.58 | -0.66 | -0.55 | -0.1 | 0.01 | -0.28 | -0.11 | -1.22 | 0.48 | 0.47 | 0.14 | -0.09 | -0.08 | -0.04 | -0.37 | -1.12 | -0.89 | -0.98 | -1.0 | 0.43 | 0.46 | 0.67 | 0.43 | 0.21 | 1.03 | 0.07 | -0.09 | 0.89 | 0.26 | 0.82 | 0.02 | -0.04 | -0.4 | -0.2 | -0.14 | -0.17 | 0.03 | -0.04 | |
| -0.06 | 1.8 | 2.44 | -6.41 | 0.04 | -0.14 | -0.79 | -0.05 | -0.69 | -0.93 | -0.53 | -0.47 | -1.22 | -1.74 | -1.29 | -0.99 | -1.06 | -1.33 | -0.97 | -0.61 | -0.56 | -0.41 | -0.38 | -0.2 | 0.58 | -0.8 | -0.92 | -0.11 | -0.65 | -1.06 | 1.0 | 0.08 | 0.82 | 0.07 | 0.42 | 1.81 | -1.28 | -1.56 | -1.31 | -1.55 | 0.76 | -0.37 | -0.19 | 0.61 | -0.75 | 0.85 | -0.42 | -0.12 | -0.78 | -0.39 | 0.03 | 0.54 | -0.15 | -0.31 | |
| 0.42 | 0.51 | 2.23 | -3.41 | -0.48 | -0.13 | 0.87 | -0.65 | 0.43 | -0.51 | -0.39 | 0.5 | -0.47 | -0.21 | -1.23 | -1.45 | -1.38 | -1.52 | -0.72 | 0.05 | -0.07 | 0.32 | -0.79 | -1.88 | 0.97 | -0.14 | -0.34 | -1.03 | -0.8 | -0.97 | -0.01 | -0.77 | -1.47 | -1.32 | -1.36 | 0.91 | -0.47 | -0.23 | -0.39 | -0.5 | 2.04 | -0.59 | -0.9 | 1.56 | -0.29 | 1.84 | -0.96 | -0.82 | -1.55 | -0.99 | -0.9 | -0.36 | -0.22 | -0.51 | |
| 0.6 | 0.02 | 2.75 | -1.36 | -2.12 | -0.48 | -0.66 | 0.85 | - | -0.96 | -2.05 | - | -0.49 | -0.74 | -1.31 | -1.85 | -1.9 | -1.41 | -1.22 | -1.1 | 0.04 | -0.4 | 0.25 | -0.05 | 1.43 | 0.63 | -0.3 | -0.44 | -0.48 | 0.01 | 0.62 | -0.57 | -0.69 | -0.8 | -0.86 | 0.34 | 0.47 | 0.54 | 0.16 | -0.12 | 0.64 | -0.24 | 0.13 | 0.65 | -0.04 | 0.88 | 0.15 | -0.07 | -0.59 | -1.05 | 0.32 | 0.05 | -0.19 | -0.2 | |
| 0.08 | 0.84 | 1.99 | -3.4 | -0.96 | -0.16 | -0.9 | 0.48 | 0.28 | 0.63 | 0.21 | 0.68 | -1.46 | 0.06 | -1.56 | -1.67 | -1.7 | -1.68 | -0.94 | 0.5 | 0.28 | 0.33 | -1.3 | -2.48 | 0.59 | 0.59 | 0.32 | -1.08 | -0.61 | -1.18 | 0.54 | -0.1 | -1.26 | -1.62 | -1.16 | 1.48 | 0.0 | 0.42 | 0.27 | 0.42 | 0.83 | 0.52 | -0.57 | 0.55 | 0.44 | 1.24 | -0.52 | -0.57 | -1.32 | -1.27 | -1.42 | -1.1 | -0.71 | -0.41 | |
| 0.51 | 0.25 | 1.83 | -3.3 | -0.56 | 0.07 | 0.48 | -0.45 | 0.27 | -0.33 | -0.3 | 0.09 | -0.53 | -0.58 | -0.67 | -0.68 | -0.64 | -0.71 | -0.2 | 0.08 | 0.07 | 0.57 | -0.46 | -1.08 | 0.62 | 0.07 | -0.23 | -0.68 | -0.33 | -0.77 | -0.04 | -0.07 | -0.97 | -0.36 | -0.8 | 1.3 | -0.14 | 0.42 | -0.16 | -0.2 | 1.2 | -0.31 | -0.62 | 0.94 | -0.24 | 1.23 | -0.69 | -0.58 | -1.09 | -0.71 | -0.56 | 0.03 | -0.02 | -0.27 | |
| -2.11 | - | -0.07 | -1.99 | -2.33 | -0.75 | 0.05 | -2.32 | - | -2.46 | - | -1.41 | 0.27 | -0.15 | -0.42 | 0.38 | -0.99 | -0.04 | -0.79 | -1.1 | -0.53 | -1.3 | 0.63 | -1.66 | 2.36 | 0.36 | 0.12 | 1.11 | -0.94 | -0.24 | 1.84 | -3.63 | -2.57 | -2.05 | -4.63 | 0.5 | 1.06 | 0.43 | 0.58 | -0.51 | 1.86 | -0.71 | 0.14 | 1.97 | -1.01 | 1.04 | -0.26 | -0.29 | 0.26 | 0.59 | -0.58 | -1.41 | -1.7 | -0.7 | |
| -1.66 | - | 2.12 | 0.19 | -3.42 | -1.72 | -1.25 | - | - | - | -0.92 | -0.28 | -0.88 | 0.51 | - | - | - | - | - | - | - | -1.17 | -1.18 | -0.38 | 2.27 | -0.07 | -1.18 | -2.27 | -0.14 | -1.58 | 1.78 | -1.0 | -2.25 | -1.65 | -1.06 | 1.98 | -0.85 | 0.73 | -0.28 | -2.37 | 3.2 | -1.6 | -1.69 | 1.94 | -0.12 | 2.13 | -3.43 | -2.82 | -1.26 | -0.74 | -2.0 | -0.23 | -0.99 | -0.35 | |
| 0.44 | 0.83 | 1.6 | -3.0 | -19.71 | -1.81 | -1.61 | -2.77 | -1.25 | - | - | -1.08 | -2.9 | -4.82 | -1.83 | -3.98 | -2.13 | -1.03 | -2.23 | -2.4 | -2.42 | -1.6 | -0.09 | -0.97 | 1.67 | -0.69 | -0.76 | 0.06 | 0.1 | -0.35 | 0.76 | -0.2 | -0.21 | -0.36 | -0.59 | 1.01 | -0.83 | -0.75 | -0.55 | -0.88 | 2.57 | -0.72 | 0.09 | 1.66 | -0.4 | 2.21 | 0.64 | 0.06 | -0.66 | -0.22 | -0.32 | 0.23 | 0.88 | 0.86 | |
| 0.07 | -0.33 | 3.13 | -1.6 | -3.28 | -1.43 | -0.48 | -0.76 | 0.19 | -0.92 | 0.5 | 0.55 | -1.21 | 0.63 | - | -1.45 | - | - | -1.83 | -1.19 | -0.57 | -0.34 | -1.24 | -0.27 | 0.33 | -0.22 | 0.31 | -0.5 | -0.58 | -0.47 | 1.23 | 0.13 | -1.02 | -2.02 | -2.75 | -1.05 | 0.56 | 0.01 | -0.13 | 0.56 | 1.08 | 0.34 | -1.0 | 1.61 | 0.36 | 0.58 | -0.75 | -1.09 | -0.4 | -0.64 | -0.82 | -0.36 | -0.47 | 0.64 | |
| 0.2 | 0.56 | 1.1 | -5.84 | 0.11 | 0.16 | 0.14 | 0.12 | 0.44 | -0.17 | 0.1 | 0.39 | -0.59 | -0.36 | -0.43 | -0.52 | -0.44 | -0.42 | 0.02 | 0.08 | 0.21 | 0.73 | -0.56 | -0.84 | 0.71 | -0.47 | -0.47 | -0.52 | -0.28 | -0.42 | 0.89 | -0.48 | -0.56 | -0.38 | -0.6 | 0.95 | -0.44 | -0.33 | -0.47 | -0.27 | 1.01 | -0.44 | -0.54 | 0.75 | -0.21 | 1.18 | -0.5 | -0.5 | -0.62 | -0.28 | -0.47 | -0.11 | -0.12 | -0.03 | |
| -0.93 | 0.37 | 1.78 | -3.63 | 0.17 | 0.1 | 0.27 | -0.25 | 0.47 | -0.35 | -0.26 | 0.3 | 0.06 | -0.31 | -0.65 | -0.76 | -0.6 | -0.72 | 0.07 | -0.07 | 0.32 | 0.04 | -0.06 | -1.12 | 0.85 | -0.93 | -0.28 | -0.39 | -0.59 | -0.57 | 1.19 | -0.33 | -0.94 | -1.01 | -0.98 | 1.03 | -1.16 | -1.2 | -0.96 | -0.48 | 1.3 | -0.59 | -0.61 | 1.01 | -0.42 | 1.33 | -0.67 | -0.5 | -0.55 | -0.19 | -0.1 | 0.22 | 0.14 | -0.02 | |
| -2.54 | -0.82 | 2.89 | 1.87 | -1.55 | -1.76 | -3.61 | -0.78 | - | - | -1.52 | - | - | -0.31 | -1.51 | - | -1.42 | -0.96 | - | -1.18 | -0.01 | -0.77 | -1.72 | -2.75 | 1.11 | 0.49 | 0.32 | -0.76 | -3.71 | -1.45 | -3.35 | -2.43 | -4.37 | -4.35 | -2.82 | 3.03 | -0.23 | 0.47 | 0.26 | -1.6 | 1.93 | -0.26 | -2.06 | 1.91 | -0.07 | 2.24 | -1.55 | 0.45 | -1.89 | -1.2 | -2.27 | -1.57 | -1.82 | -3.09 | |
| -2.09 | 0.23 | 2.54 | -2.6 | -2.07 | -1.31 | -1.57 | -3.72 | -2.45 | -3.88 | -4.72 | -2.02 | -2.3 | -1.39 | -2.95 | -2.41 | -2.64 | -2.93 | -3.62 | -3.11 | -2.14 | -1.63 | -0.31 | -1.47 | 1.37 | 0.75 | -0.25 | -1.11 | -1.18 | -0.57 | 0.79 | -0.87 | -0.92 | -0.8 | -1.04 | 1.72 | -0.29 | 0.32 | 0.02 | -0.5 | 2.21 | -0.34 | -0.69 | 2.25 | 0.12 | 2.02 | -0.91 | -0.51 | -0.24 | 0.09 | 0.04 | 0.35 | 0.41 | 0.67 | |
| 0.6 | 0.91 | 1.13 | -2.96 | 0.51 | 0.39 | 0.22 | 0.16 | -0.04 | -0.69 | -0.31 | 0.16 | -1.05 | -0.32 | -0.23 | 0.08 | -0.13 | -0.26 | 0.57 | 0.16 | -0.31 | -0.03 | -0.46 | -0.85 | -0.31 | 0.5 | -0.26 | -0.07 | -0.39 | -0.18 | -0.1 | -1.48 | -0.1 | -0.74 | -0.16 | -0.38 | 0.66 | 0.31 | 0.48 | 0.13 | 0.53 | 0.38 | -0.05 | 0.11 | 0.01 | 0.02 | 0.18 | -0.11 | -0.22 | -0.26 | -0.16 | -0.39 | -0.33 | -0.58 | |
| -0.35 | 1.71 | 2.64 | -4.72 | 0.12 | -0.14 | -0.48 | -0.82 | -0.21 | -0.98 | -0.88 | -0.4 | -1.43 | -1.83 | -0.76 | -0.64 | -0.85 | -0.76 | -0.14 | -0.57 | -0.75 | -0.54 | -0.97 | -0.69 | 1.27 | -0.97 | -0.76 | -0.84 | -1.06 | -0.99 | 0.7 | -1.45 | -0.4 | -0.85 | -0.46 | 1.37 | -0.92 | -1.01 | -1.03 | -1.08 | 1.66 | -0.76 | -1.03 | 1.57 | -0.83 | 2.04 | -1.02 | -1.07 | -1.01 | -0.86 | -0.69 | -0.47 | -0.1 | -0.2 | |
| -1.64 | 0.52 | 3.55 | 0.58 | 0.24 | -3.82 | -1.65 | - | -1.25 | - | -1.94 | - | -3.41 | -1.9 | - | - | -2.69 | -2.85 | - | -1.63 | - | 0.81 | -1.68 | -4.44 | 0.13 | -0.15 | -1.43 | -4.56 | -1.96 | -2.69 | -1.44 | -0.0 | - | -3.03 | -3.63 | 2.93 | -0.52 | 0.63 | -0.81 | -2.7 | 2.99 | -1.1 | -1.39 | 1.21 | -0.26 | 2.39 | - | -1.81 | -4.64 | -2.59 | -3.1 | -4.46 | -0.53 | -2.36 | |
| -0.25 | 1.36 | 3.24 | -5.01 | -1.51 | -0.42 | -0.11 | -1.36 | -0.74 | -1.55 | -1.4 | -1.39 | -1.25 | -2.0 | -1.51 | -1.71 | -1.86 | -1.75 | -1.49 | -1.14 | -1.16 | -0.65 | -0.68 | -2.33 | 1.62 | -1.62 | -1.12 | -1.38 | -1.0 | -1.6 | -0.13 | -1.9 | -1.89 | -1.62 | -2.14 | 2.57 | -1.2 | -0.98 | -1.54 | -1.34 | 1.98 | -1.32 | -1.37 | 1.74 | -1.23 | 2.06 | -1.36 | -1.51 | -2.48 | -2.11 | -1.55 | -0.09 | 0.23 | 0.51 | |
| -0.52 | 0.04 | 0.92 | -2.67 | -1.11 | -0.31 | 0.16 | -1.35 | -0.96 | -1.69 | -1.53 | -1.46 | -1.45 | -0.29 | -0.51 | -0.6 | -0.42 | -0.78 | -0.26 | -1.35 | -1.59 | -0.14 | 0.17 | -1.04 | 1.08 | 0.79 | -0.23 | -0.11 | 0.22 | -0.01 | 0.16 | -0.88 | -1.05 | -0.95 | -1.29 | 0.76 | 0.62 | 0.76 | 0.6 | 0.23 | 0.85 | 0.27 | -0.02 | 1.26 | 0.76 | 0.82 | 0.23 | 0.32 | 0.18 | 0.01 | 0.28 | 0.36 | 0.29 | 0.48 | |
| -0.66 | - | 0.6 | 1.9 | -2.33 | -0.49 | -1.58 | -1.02 | - | - | - | - | -0.64 | -1.41 | - | - | - | - | -0.52 | - | - | - | -2.19 | - | 4.07 | -2.21 | -1.87 | - | -1.55 | -1.42 | 2.56 | - | -2.58 | - | - | -0.33 | - | -1.19 | -3.66 | -2.62 | 2.72 | -2.68 | -3.79 | 2.06 | -1.02 | 2.58 | -3.69 | -2.64 | -0.45 | -3.38 | - | -2.24 | - | -3.21 | |
| -1.45 | - | 3.64 | 0.8 | -5.23 | -2.82 | - | - | - | - | - | -1.55 | -2.58 | -3.57 | -3.17 | - | -3.09 | - | - | -2.88 | - | -2.44 | -4.01 | -4.57 | 3.4 | -1.23 | -3.2 | -4.73 | -2.2 | -3.64 | 1.75 | - | -2.26 | -4.67 | - | 1.46 | -3.99 | -1.23 | -2.17 | - | 2.86 | -4.94 | -3.51 | 2.17 | -2.88 | 2.75 | -3.98 | -4.92 | -3.18 | - | -3.61 | -2.86 | -2.31 | -2.87 | |
| -0.9 | 1.63 | 4.26 | -0.64 | -3.06 | -1.36 | -0.7 | -1.69 | -0.83 | -2.79 | -2.14 | -1.34 | -1.67 | -1.95 | -4.13 | -3.54 | -4.08 | -3.71 | -3.72 | -1.13 | -2.05 | 0.01 | -3.38 | -2.94 | 1.8 | -2.52 | -2.99 | -3.67 | -2.65 | -3.59 | 2.67 | -0.63 | -2.96 | -1.29 | -3.3 | -1.97 | -2.91 | -1.88 | -2.7 | -3.36 | 1.96 | -4.14 | -3.72 | 1.94 | -2.51 | 1.64 | -3.65 | -3.36 | -3.7 | -4.34 | -3.48 | -2.42 | -1.89 | -1.54 | |
| -2.18 | 1.66 | 4.32 | -1.34 | -4.25 | -3.09 | -2.78 | -3.36 | -1.88 | -3.22 | -3.03 | -2.73 | -3.16 | -3.98 | -5.17 | -4.67 | -5.94 | -4.56 | -5.37 | -3.13 | -3.2 | -3.17 | -4.11 | -4.52 | 0.84 | -2.19 | -3.22 | -4.67 | -3.94 | -4.67 | 1.16 | -2.28 | -4.55 | -2.99 | -4.36 | 2.88 | -2.52 | -1.74 | -2.77 | -3.92 | 2.47 | -4.87 | -4.48 | 2.08 | -3.2 | 2.28 | -4.66 | -4.19 | -4.21 | -4.32 | -4.44 | -3.21 | -2.84 | -2.72 | |
| -2.05 | -0.76 | 3.33 | -0.2 | -3.89 | -3.88 | -1.64 | -0.21 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0.09 | 0.02 | 2.38 | 0.52 | -0.22 | -2.35 | -1.97 | - | 0.98 | -0.51 | - | -1.38 | - | 1.89 | -2.69 | -1.55 | 0.57 | -1.47 | 2.33 | -2.55 | -2.58 | 3.04 | -1.51 | 2.42 | -1.64 | -2.5 | - | -2.46 | -1.47 | - | 0.22 | -2.12 |
Dark gray cells indicate values where the raw expression is zero (cannot be log-transformed). Blue cells indicate samples where the expression of the gene is below average and red cells indicate the gene is expressed above average in the sample. White cells are average.