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GO:0004252: serine-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]


There are 2426 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_161 Arabidopsis thaliana 5.66 % 0.000318 0.032004
Cluster_146 Arabidopsis thaliana 2.7 % 0.00272 0.014363
Cluster_190 Arabidopsis thaliana 1.78 % 0.008745 0.049571
Cluster_33 Chlamydomonas reinhardtii 2.22 % 0.024683 0.042141
Cluster_240 Marchantia polymorpha 50.0 % 0.002984 0.037304
Cluster_213 Zygnema circumcarinatum 100.0 % 4e-06 2.7e-05
Cluster_85 Zygnema circumcarinatum 10.2 % 0.0 6e-06
Sequences (2426) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms