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GO:0008534: oxidized purine nucleobase lesion DNA N-glycosylase activity (Molecular function)

"Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296]


There are 220 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_145 Arabidopsis thaliana 0.56 % 0.006473 0.035442
Sequences (220) (download table)

InterPro Domains

GO Terms

Family Terms