Cre01.g017450

Description : Cell cycle.interphase.DNA replication.elongation.DNA polymerase alpha complex.POLA2 replication fork tethering component

Gene families : OG_01_0008835 (OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci) Phylogenetic Tree(s): OG0008835_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Cre01.g017450
Cluster	HCCA: Cluster_92

Target	Alias	Description	ECC score	Gene Family Method
AT1G67630	No alias	DNA polymerase alpha 2	0.04	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci
Mp6g03190.1	No alias	replication fork tethering component POLA2 of DNA...	0.06	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci
Pp3c10_15960V3.1	No alias	DNA polymerase alpha 2	0.03	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	HCCA
CC	GO:0000808	origin recognition complex	IEP	HCCA
MF	GO:0003690	double-stranded DNA binding	IEP	HCCA
MF	GO:0003896	DNA primase activity	IEP	HCCA
MF	GO:0003909	DNA ligase activity	IEP	HCCA
MF	GO:0003910	DNA ligase (ATP) activity	IEP	HCCA
MF	GO:0003916	DNA topoisomerase activity	IEP	HCCA
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	HCCA
MF	GO:0005524	ATP binding	IEP	HCCA
CC	GO:0005634	nucleus	IEP	HCCA
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	HCCA
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	HCCA
BP	GO:0006259	DNA metabolic process	IEP	HCCA
BP	GO:0006265	DNA topological change	IEP	HCCA
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	HCCA
BP	GO:0006270	DNA replication initiation	IEP	HCCA
BP	GO:0006275	regulation of DNA replication	IEP	HCCA
BP	GO:0006281	DNA repair	IEP	HCCA
BP	GO:0006298	mismatch repair	IEP	HCCA
BP	GO:0006310	DNA recombination	IEP	HCCA
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	HCCA
BP	GO:0006950	response to stress	IEP	HCCA
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	HCCA
BP	GO:0006996	organelle organization	IEP	HCCA
BP	GO:0007062	sister chromatid cohesion	IEP	HCCA
BP	GO:0007064	mitotic sister chromatid cohesion	IEP	HCCA
MF	GO:0008092	cytoskeletal protein binding	IEP	HCCA
BP	GO:0008156	negative regulation of DNA replication	IEP	HCCA
BP	GO:0009890	negative regulation of biosynthetic process	IEP	HCCA
BP	GO:0009892	negative regulation of metabolic process	IEP	HCCA
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	HCCA
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	HCCA
MF	GO:0015631	tubulin binding	IEP	HCCA
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	HCCA
MF	GO:0017076	purine nucleotide binding	IEP	HCCA
BP	GO:0022402	cell cycle process	IEP	HCCA
MF	GO:0030554	adenyl nucleotide binding	IEP	HCCA
MF	GO:0030983	mismatched DNA binding	IEP	HCCA
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	HCCA
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	HCCA
CC	GO:0031390	Ctf18 RFC-like complex	IEP	HCCA
MF	GO:0032553	ribonucleotide binding	IEP	HCCA
MF	GO:0032555	purine ribonucleotide binding	IEP	HCCA
MF	GO:0032559	adenyl ribonucleotide binding	IEP	HCCA
BP	GO:0033554	cellular response to stress	IEP	HCCA
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	HCCA
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	HCCA
MF	GO:0036094	small molecule binding	IEP	HCCA
MF	GO:0043015	gamma-tubulin binding	IEP	HCCA
MF	GO:0043168	anion binding	IEP	HCCA
CC	GO:0043226	organelle	IEP	HCCA
CC	GO:0043227	membrane-bounded organelle	IEP	HCCA
CC	GO:0043229	intracellular organelle	IEP	HCCA
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	HCCA
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	HCCA
BP	GO:0046483	heterocycle metabolic process	IEP	HCCA
BP	GO:0048478	replication fork protection	IEP	HCCA
BP	GO:0048523	negative regulation of cellular process	IEP	HCCA
BP	GO:0050896	response to stimulus	IEP	HCCA
BP	GO:0051276	chromosome organization	IEP	HCCA
BP	GO:0051716	cellular response to stimulus	IEP	HCCA
BP	GO:0071103	DNA conformation change	IEP	HCCA
BP	GO:0090304	nucleic acid metabolic process	IEP	HCCA
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	HCCA
MF	GO:0097367	carbohydrate derivative binding	IEP	HCCA
MF	GO:1901265	nucleoside phosphate binding	IEP	HCCA
BP	GO:1901360	organic cyclic compound metabolic process	IEP	HCCA
BP	GO:1903047	mitotic cell cycle process	IEP	HCCA
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	HCCA
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR013627	Pol_alpha_B_N	28	270
IPR007185	DNA_pol_a/d/e_bsu	451	665

External Links

No external refs found!

Cre01.g017450

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation