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GO:0003918: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2." [PMID:8811192]


There are 1079 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_228 Arabidopsis thaliana 1.39 % 0.000946 0.024375
Cluster_137 Chlamydomonas reinhardtii 1.82 % 0.012344 0.030762
Cluster_6 Marchantia polymorpha 1.0 % 0.020439 0.03425
Cluster_51 Marchantia polymorpha 2.11 % 0.000141 0.003008
Cluster_150 Zygnema circumcarinatum 1.18 % 0.012586 0.04202
Sequences (1079) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms