AT2G32000

Description : DNA topoisomerase, type IA, core

Gene families : OG_01_0005895 (OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci) Phylogenetic Tree(s): OG0005895_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT2G32000
Cluster	HCCA: Cluster_220

Target	Alias	Description	ECC score	Gene Family Method	Actions
Mp1g10070.1	No alias	topoisomerase component TOP3b of TDRD3-TOP3B...	0.02	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci
Zci_07238.1	No alias	type-1A topoisomerase TOP3b	0.02	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	ISS	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	ISS	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005576	extracellular region	ISM	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	ISS	Interproscan
BP	GO:0006268	DNA unwinding involved in DNA replication	ISS	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009314	response to radiation	None	Extended
BP	GO:0009416	response to light stimulus	None	Extended
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0009648	photoperiodism	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0022414	reproductive process	None	Extended
BP	GO:0032392	DNA geometric change	None	Extended
BP	GO:0032508	DNA duplex unwinding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0048573	photoperiodism, flowering	RCA	Interproscan
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000003	reproduction	IEP	HCCA
CC	GO:0000145	exocyst	IEP	HCCA
CC	GO:0000151	ubiquitin ligase complex	IEP	HCCA
MF	GO:0000166	nucleotide binding	IEP	HCCA
BP	GO:0000278	mitotic cell cycle	IEP	HCCA
BP	GO:0000374	Group III intron splicing	IEP	HCCA
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	HCCA
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	HCCA
CC	GO:0000932	P-body	IEP	HCCA
BP	GO:0003002	regionalization	IEP	HCCA
MF	GO:0003724	RNA helicase activity	IEP	HCCA
MF	GO:0003725	double-stranded RNA binding	IEP	HCCA
MF	GO:0003964	RNA-directed DNA polymerase activity	IEP	HCCA
MF	GO:0004386	helicase activity	IEP	HCCA
MF	GO:0004525	ribonuclease III activity	IEP	HCCA
MF	GO:0005524	ATP binding	IEP	HCCA
CC	GO:0005634	nucleus	IEP	HCCA
BP	GO:0006278	RNA-dependent DNA biosynthetic process	IEP	HCCA
BP	GO:0006310	DNA recombination	IEP	HCCA
BP	GO:0006349	regulation of gene expression by genetic imprinting	IEP	HCCA
BP	GO:0006396	RNA processing	IEP	HCCA
BP	GO:0006464	cellular protein modification process	IEP	HCCA
BP	GO:0006479	protein methylation	IEP	HCCA
BP	GO:0006508	proteolysis	IEP	HCCA
BP	GO:0006885	regulation of pH	IEP	HCCA
BP	GO:0006892	post-Golgi vesicle-mediated transport	IEP	HCCA
BP	GO:0006896	Golgi to vacuole transport	IEP	HCCA
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	HCCA
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	HCCA
BP	GO:0007010	cytoskeleton organization	IEP	HCCA
BP	GO:0007049	cell cycle	IEP	HCCA
BP	GO:0007131	reciprocal meiotic recombination	IEP	HCCA
BP	GO:0007389	pattern specification process	IEP	HCCA
MF	GO:0008186	ATP-dependent activity, acting on RNA	IEP	HCCA
BP	GO:0008213	protein alkylation	IEP	HCCA
BP	GO:0009606	tropism	IEP	HCCA
BP	GO:0009629	response to gravity	IEP	HCCA
BP	GO:0009630	gravitropism	IEP	HCCA
BP	GO:0009639	response to red or far red light	IEP	HCCA
BP	GO:0009640	photomorphogenesis	IEP	HCCA
BP	GO:0009791	post-embryonic development	IEP	HCCA
BP	GO:0009887	animal organ morphogenesis	IEP	HCCA
BP	GO:0009888	tissue development	IEP	HCCA
BP	GO:0009909	regulation of flower development	IEP	HCCA
BP	GO:0009910	negative regulation of flower development	IEP	HCCA
BP	GO:0009956	radial pattern formation	IEP	HCCA
BP	GO:0010018	far-red light signaling pathway	IEP	HCCA
BP	GO:0010091	trichome branching	IEP	HCCA
BP	GO:0010212	response to ionizing radiation	IEP	HCCA
BP	GO:0010305	leaf vascular tissue pattern formation	IEP	HCCA
BP	GO:0010496	intercellular transport	IEP	HCCA
BP	GO:0010603	regulation of cytoplasmic mRNA processing body assembly	IEP	HCCA
BP	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly	IEP	HCCA
BP	GO:0010638	positive regulation of organelle organization	IEP	HCCA
MF	GO:0015386	potassium:proton antiporter activity	IEP	HCCA
BP	GO:0016070	RNA metabolic process	IEP	HCCA
MF	GO:0016462	pyrophosphatase activity	IEP	HCCA
BP	GO:0016567	protein ubiquitination	IEP	HCCA
BP	GO:0016570	histone modification	IEP	HCCA
BP	GO:0016571	histone methylation	IEP	HCCA
BP	GO:0016579	protein deubiquitination	IEP	HCCA
CC	GO:0016592	mediator complex	IEP	HCCA
MF	GO:0016805	dipeptidase activity	IEP	HCCA
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	HCCA
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	HCCA
MF	GO:0016887	ATP hydrolysis activity	IEP	HCCA
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEP	HCCA
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	HCCA
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	HCCA
BP	GO:0017148	negative regulation of translation	IEP	HCCA
BP	GO:0022406	membrane docking	IEP	HCCA
MF	GO:0022821	potassium ion antiporter activity	IEP	HCCA
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	IEP	HCCA
BP	GO:0030036	actin cytoskeleton organization	IEP	HCCA
MF	GO:0030554	adenyl nucleotide binding	IEP	HCCA
BP	GO:0030641	regulation of cellular pH	IEP	HCCA
BP	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA	IEP	HCCA
CC	GO:0031209	SCAR complex	IEP	HCCA
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	HCCA
BP	GO:0032259	methylation	IEP	HCCA
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	HCCA
BP	GO:0032446	protein modification by small protein conjugation	IEP	HCCA
BP	GO:0032501	multicellular organismal process	IEP	HCCA
BP	GO:0032504	multicellular organism reproduction	IEP	HCCA
MF	GO:0032559	adenyl ribonucleotide binding	IEP	HCCA
BP	GO:0032956	regulation of actin cytoskeleton organization	IEP	HCCA
BP	GO:0032970	regulation of actin filament-based process	IEP	HCCA
BP	GO:0033043	regulation of organelle organization	IEP	HCCA
BP	GO:0033044	regulation of chromosome organization	IEP	HCCA
BP	GO:0033962	P-body assembly	IEP	HCCA
MF	GO:0034061	DNA polymerase activity	IEP	HCCA
BP	GO:0034249	negative regulation of cellular amide metabolic process	IEP	HCCA
CC	GO:0035770	ribonucleoprotein granule	IEP	HCCA
BP	GO:0035825	homologous recombination	IEP	HCCA
MF	GO:0036094	small molecule binding	IEP	HCCA
BP	GO:0036211	protein modification process	IEP	HCCA
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	IEP	HCCA
BP	GO:0040029	regulation of gene expression, epigenetic	IEP	HCCA
BP	GO:0042753	positive regulation of circadian rhythm	IEP	HCCA
CC	GO:0043226	organelle	IEP	HCCA
CC	GO:0043227	membrane-bounded organelle	IEP	HCCA
CC	GO:0043229	intracellular organelle	IEP	HCCA
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	HCCA
BP	GO:0043412	macromolecule modification	IEP	HCCA
BP	GO:0043414	macromolecule methylation	IEP	HCCA
BP	GO:0044089	positive regulation of cellular component biogenesis	IEP	HCCA
MF	GO:0046983	protein dimerization activity	IEP	HCCA
BP	GO:0048278	vesicle docking	IEP	HCCA
BP	GO:0048518	positive regulation of biological process	IEP	HCCA
BP	GO:0048519	negative regulation of biological process	IEP	HCCA
BP	GO:0048522	positive regulation of cellular process	IEP	HCCA
BP	GO:0048580	regulation of post-embryonic development	IEP	HCCA
BP	GO:0048581	negative regulation of post-embryonic development	IEP	HCCA
BP	GO:0048700	acquisition of desiccation tolerance in seed	IEP	HCCA
BP	GO:0048831	regulation of shoot system development	IEP	HCCA
BP	GO:0051093	negative regulation of developmental process	IEP	HCCA
BP	GO:0051125	regulation of actin nucleation	IEP	HCCA
BP	GO:0051127	positive regulation of actin nucleation	IEP	HCCA
BP	GO:0051128	regulation of cellular component organization	IEP	HCCA
BP	GO:0051130	positive regulation of cellular component organization	IEP	HCCA
BP	GO:0051241	negative regulation of multicellular organismal process	IEP	HCCA
BP	GO:0051453	regulation of intracellular pH	IEP	HCCA
BP	GO:0051493	regulation of cytoskeleton organization	IEP	HCCA
BP	GO:0051495	positive regulation of cytoskeleton organization	IEP	HCCA
BP	GO:0055067	monovalent inorganic cation homeostasis	IEP	HCCA
BP	GO:0070646	protein modification by small protein removal	IEP	HCCA
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	HCCA
BP	GO:0071490	cellular response to far red light	IEP	HCCA
BP	GO:0071514	genetic imprinting	IEP	HCCA
BP	GO:0071897	DNA biosynthetic process	IEP	HCCA
CC	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	IEP	HCCA
BP	GO:0080171	lytic vacuole organization	IEP	HCCA
BP	GO:0090057	root radial pattern formation	IEP	HCCA
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	IEP	HCCA
BP	GO:0090351	seedling development	IEP	HCCA
BP	GO:0097439	acquisition of desiccation tolerance	IEP	HCCA
BP	GO:0110053	regulation of actin filament organization	IEP	HCCA
BP	GO:0110154	RNA decapping	IEP	HCCA
BP	GO:0110156	methylguanosine-cap decapping	IEP	HCCA
BP	GO:0140029	exocytic process	IEP	HCCA
BP	GO:0140056	organelle localization by membrane tethering	IEP	HCCA
BP	GO:0140527	reciprocal homologous recombination	IEP	HCCA
MF	GO:0140657	ATP-dependent activity	IEP	HCCA
MF	GO:1901265	nucleoside phosphate binding	IEP	HCCA
BP	GO:1902115	regulation of organelle assembly	IEP	HCCA
BP	GO:1902117	positive regulation of organelle assembly	IEP	HCCA
BP	GO:1902903	regulation of supramolecular fiber organization	IEP	HCCA
BP	GO:1902905	positive regulation of supramolecular fiber organization	IEP	HCCA
BP	GO:2000026	regulation of multicellular organismal development	IEP	HCCA
BP	GO:2000241	regulation of reproductive process	IEP	HCCA
BP	GO:2000242	negative regulation of reproductive process	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	7	150
IPR013497	Topo_IA_cen	166	577

External Links

PLAZA 3.0 Dicots	AT2G32000

AT2G32000

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation