Zci_01358.2

Description : DNA topoisomerase (TOP1)

Gene families : OG_01_0003603 (OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci) Phylogenetic Tree(s): OG0003603_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Zci_01358.2
Cluster	HCCA: Cluster_141

Target	Alias	Description	ECC score	Gene Family Method	Actions
Cre03.g178600	No alias	Cell cycle.interphase.DNA replication.preinitiation.TOP1...	0.02	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEP	HCCA
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	HCCA
MF	GO:0003723	RNA binding	IEP	HCCA
MF	GO:0004180	carboxypeptidase activity	IEP	HCCA
MF	GO:0004185	serine-type carboxypeptidase activity	IEP	HCCA
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEP	HCCA
MF	GO:0005215	transporter activity	IEP	HCCA
BP	GO:0009451	RNA modification	IEP	HCCA
BP	GO:0009966	regulation of signal transduction	IEP	HCCA
MF	GO:0009982	pseudouridine synthase activity	IEP	HCCA
BP	GO:0010646	regulation of cell communication	IEP	HCCA
CC	GO:0016020	membrane	IEP	HCCA
MF	GO:0016866	intramolecular transferase activity	IEP	HCCA
MF	GO:0022857	transmembrane transporter activity	IEP	HCCA
BP	GO:0023051	regulation of signaling	IEP	HCCA
MF	GO:0030234	enzyme regulator activity	IEP	HCCA
MF	GO:0030695	GTPase regulator activity	IEP	HCCA
BP	GO:0032012	regulation of ARF protein signal transduction	IEP	HCCA
BP	GO:0043412	macromolecule modification	IEP	HCCA
BP	GO:0046578	regulation of Ras protein signal transduction	IEP	HCCA
BP	GO:0048583	regulation of response to stimulus	IEP	HCCA
BP	GO:0050789	regulation of biological process	IEP	HCCA
BP	GO:0050794	regulation of cellular process	IEP	HCCA
BP	GO:0051056	regulation of small GTPase mediated signal transduction	IEP	HCCA
MF	GO:0051499	D-aminoacyl-tRNA deacylase activity	IEP	HCCA
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	HCCA
BP	GO:0055085	transmembrane transport	IEP	HCCA
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	HCCA
BP	GO:0065007	biological regulation	IEP	HCCA
MF	GO:0070008	serine-type exopeptidase activity	IEP	HCCA
MF	GO:0098772	molecular function regulator	IEP	HCCA
BP	GO:1902531	regulation of intracellular signal transduction	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR025834	TopoI_C_dom	435	503
IPR008336	TopoI_DNA-bd_euk	1	171
IPR013500	TopoI_cat_euk	174	396

External Links

No external refs found!

Zci_01358.2

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation