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GO:0016829: lyase activity (Molecular function)

"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [ISBN:0198547684]


There are 4355 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_154 Arabidopsis thaliana 4.2 % 0.006929 0.028057
Cluster_397 Arabidopsis thaliana 100.0 % 1e-06 3e-06
Cluster_48 Arabidopsis thaliana 6.18 % 2e-06 1.6e-05
Cluster_69 Arabidopsis thaliana 7.89 % 0.000114 0.001072
Cluster_17 Arabidopsis thaliana 6.14 % 0.000151 0.001213
Cluster_122 Chlamydomonas reinhardtii 8.7 % 0.000929 0.007095
Cluster_74 Chlamydomonas reinhardtii 6.12 % 0.011173 0.031424
Cluster_33 Chlamydomonas reinhardtii 8.89 % 2e-06 7e-06
Cluster_51 Chlamydomonas reinhardtii 8.33 % 6.1e-05 0.000765
Cluster_153 Chlamydomonas reinhardtii 6.4 % 2.5e-05 0.00025
Cluster_84 Chlamydomonas reinhardtii 5.36 % 0.000689 0.018271
Cluster_169 Chlamydomonas reinhardtii 7.02 % 0.002074 0.020443
Cluster_208 Chlamydomonas reinhardtii 50.0 % 0.01885 0.034374
Cluster_142 Chlamydomonas reinhardtii 21.82 % 0.0 0.0
Cluster_31 Chlamydomonas reinhardtii 5.26 % 0.016799 0.03624
Cluster_14 Chlamydomonas reinhardtii 5.48 % 7.6e-05 0.000407
Cluster_321 Marchantia polymorpha 50.0 % 0.009555 0.025479
Cluster_11 Marchantia polymorpha 3.68 % 0.000133 0.000746
Cluster_43 Marchantia polymorpha 5.88 % 0.000317 0.009841
Cluster_53 Physcomitrella patens 2.99 % 0.001878 0.011423
Cluster_121 Physcomitrella patens 1.32 % 0.009268 0.017137
Cluster_59 Physcomitrella patens 3.08 % 0.001769 0.013442
Cluster_38 Zygnema circumcarinatum 2.04 % 0.005577 0.039819
Cluster_13 Zygnema circumcarinatum 3.54 % 0.000754 0.036755
Sequences (4355) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms