Zci_13035.1

Description : dihydrofolate reductase

Gene families : OG_01_0004795 (OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci) Phylogenetic Tree(s): OG0004795_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Zci_13035.1
Cluster	HCCA: Cluster_165

Target	Alias	Description	ECC score	Gene Family Method	Actions
AT2G16370	No alias	thymidylate synthase 1	0.02	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci
Cre17.g715900	No alias	Coenzyme metabolism.tetrahydrofolate...	0.02	OrthoFinder output from Ath, Cre, Mpo, Ppa and Zci

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004146	dihydrofolate reductase activity	IEA	Interproscan
BP	GO:0006575	cellular modified amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006760	folic acid-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009396	folic acid-containing compound biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	None	Extended
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042398	cellular modified amino acid biosynthetic process	None	Extended
BP	GO:0042558	pteridine-containing compound metabolic process	None	Extended
BP	GO:0042559	pteridine-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046653	tetrahydrofolate metabolic process	None	Extended
BP	GO:0046654	tetrahydrofolate biosynthetic process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003676	nucleic acid binding	IEP	HCCA
MF	GO:0003746	translation elongation factor activity	IEP	HCCA
MF	GO:0005488	binding	IEP	HCCA
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	HCCA
BP	GO:0006259	DNA metabolic process	IEP	HCCA
BP	GO:0006275	regulation of DNA replication	IEP	HCCA
BP	GO:0006353	DNA-templated transcription, termination	IEP	HCCA
BP	GO:0006414	translational elongation	IEP	HCCA
BP	GO:0008156	negative regulation of DNA replication	IEP	HCCA
MF	GO:0008270	zinc ion binding	IEP	HCCA
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	HCCA
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	HCCA
BP	GO:0009890	negative regulation of biosynthetic process	IEP	HCCA
BP	GO:0009892	negative regulation of metabolic process	IEP	HCCA
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	HCCA
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	HCCA
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	HCCA
MF	GO:0016840	carbon-nitrogen lyase activity	IEP	HCCA
MF	GO:0016843	amine-lyase activity	IEP	HCCA
MF	GO:0016844	strictosidine synthase activity	IEP	HCCA
MF	GO:0019899	enzyme binding	IEP	HCCA
MF	GO:0031267	small GTPase binding	IEP	HCCA
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	HCCA
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	HCCA
BP	GO:0032392	DNA geometric change	IEP	HCCA
BP	GO:0032508	DNA duplex unwinding	IEP	HCCA
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	HCCA
MF	GO:0043015	gamma-tubulin binding	IEP	HCCA
MF	GO:0043167	ion binding	IEP	HCCA
MF	GO:0043169	cation binding	IEP	HCCA
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	HCCA
MF	GO:0046872	metal ion binding	IEP	HCCA
MF	GO:0046914	transition metal ion binding	IEP	HCCA
BP	GO:0048478	replication fork protection	IEP	HCCA
BP	GO:0048523	negative regulation of cellular process	IEP	HCCA
MF	GO:0050661	NADP binding	IEP	HCCA
MF	GO:0051020	GTPase binding	IEP	HCCA
BP	GO:0071103	DNA conformation change	IEP	HCCA
MF	GO:0071949	FAD binding	IEP	HCCA
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	HCCA
MF	GO:0097159	organic cyclic compound binding	IEP	HCCA
MF	GO:1901363	heterocyclic compound binding	IEP	HCCA
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	HCCA
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR023451	Thymidate_synth/dCMP_Mease_dom	316	381
IPR023451	Thymidate_synth/dCMP_Mease_dom	412	645
IPR001796	DHFR_dom	72	198

External Links

No external refs found!

Zci_13035.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation